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PDA Journal of Pharmaceutical Science and Technology

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Nitrogen Dioxide sterilization follows log-linear microbial inactivation kinetics using Geobacillus stearothermophilus biological indicators

Thomas P Richards, Delaney Lisco, Tiffany Bianchi, Gabriele Shahine, Huyen Nyugen, Natalie Simmons, Sylvie Dufresne and David Opie
PDA Journal of Pharmaceutical Science and Technology June 2025, pdajpst.2024.012997; DOI: https://doi.org/10.5731/pdajpst.2024.012997
Thomas P Richards
1 IM3 Inc.;
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  • For correspondence: trichards@im3consultinggroup.com
Delaney Lisco
2 Noxilizer, Inc.
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  • For correspondence: dlisco@noxilizer.com
Tiffany Bianchi
2 Noxilizer, Inc.
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  • For correspondence: tbianci@noxilizer.com
Gabriele Shahine
2 Noxilizer, Inc.
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  • For correspondence: gshahine@noxilizer.com
Huyen Nyugen
2 Noxilizer, Inc.
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  • For correspondence: hnyugen@noxilizer.com
Natalie Simmons
2 Noxilizer, Inc.
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  • For correspondence: nsimmons@noxilizer.com
Sylvie Dufresne
1 IM3 Inc.;
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  • For correspondence: sdufresne@im3consultinggroup.com
David Opie
2 Noxilizer, Inc.
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  • For correspondence: dopie@noxilizer.com
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PDA Journal of Pharmaceutical Science and Technology: 79 (3)
PDA Journal of Pharmaceutical Science and Technology
Vol. 79, Issue 3
May/June 2025
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Nitrogen Dioxide sterilization follows log-linear microbial inactivation kinetics using Geobacillus stearothermophilus biological indicators
Thomas P Richards, Delaney Lisco, Tiffany Bianchi, Gabriele Shahine, Huyen Nyugen, Natalie Simmons, Sylvie Dufresne, David Opie
PDA Journal of Pharmaceutical Science and Technology Jun 2025, pdajpst.2024.012997; DOI: 10.5731/pdajpst.2024.012997

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Nitrogen Dioxide sterilization follows log-linear microbial inactivation kinetics using Geobacillus stearothermophilus biological indicators
Thomas P Richards, Delaney Lisco, Tiffany Bianchi, Gabriele Shahine, Huyen Nyugen, Natalie Simmons, Sylvie Dufresne, David Opie
PDA Journal of Pharmaceutical Science and Technology Jun 2025, pdajpst.2024.012997; DOI: 10.5731/pdajpst.2024.012997
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Keywords

  • Inactivation Kinetics
  • Nitrogen Dioxide
  • Sterility Assurance
  • Sterility Test
  • Terminal Sterilization

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