Abstract
While conducting long term bacteria challenge tests of 0.2-µ.m rated sterilizing grade filters which retained 100% of the standard challenge organism P. diminuta, it was discovered that several species of indigenous water bacteria were not completely retained by these filters. This finding has been confirmed for a variety of commercially available Q.2-µm rated disc and cartridge filters. Filters were challenged with wellwater which contained naturally occurring bacterial species. The challenge system included a prefilter to remove debris and large microorganisms, the test filter, and an analysis membrane filter to monitor the total effluent. Influent bacteria levels were also
- Received November 1, 1979.
- Accepted November 16, 1979.
- Copyright © Parenteral Drug Association. All rights reserved.
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