Abstract
A statistical model is proposed to explain the accelerated stability assays that justify the Garrett method, based on the proportionality of the errors. This model permits us to assay the fitting of the experimental observations for the Arrhenius equation. An application is illustrated with the study of the accelerated stability of a solution of procaine chlorohydrate at pH 7.5, where it was found that in the temperature range of 21.5-80 °C the fitting of the Arrhenius equation was satisfactory.
- Received November 20, 1985.
- Accepted April 27, 1986.
- Copyright © Parenteral Drug Association. All rights reserved.
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