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Research ArticleRESEARCH

Polymeric Micelles of Ammonium Palmitoyl Glycol Chitosan and Solubilization of Camptothecin

Nazar M. Ranjha
PDA Journal of Pharmaceutical Science and Technology January 2009, 63 (1) 81-87;
Nazar M. Ranjha
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References

  1. 1.↵
    1. Katoka K.,
    2. Kwon G. S.,
    3. Yokoyama M.,
    4. Okano T.,
    5. Sakurai Y.
    Block copolymers as vehicle for drug delivery. J. Controlled Release 1993, 24, 119– 132.
    OpenUrlCrossRefWeb of Science
  2. 2.↵
    1. Kwon G. S.,
    2. Katoka K.
    Block copolymer micelles as long circulating drug vehicles. Adv. Drug Deliv. Rev. 1995, 6, 295– 305.
    OpenUrl
  3. 3.↵
    1. Kwon G. S.,
    2. Naito M.,
    3. Yokoyama M.,
    4. Okano T.,
    5. Sakurai Y.,
    6. Kataoka K.
    Micelles based on ab block polymers of poly(ethylene oxide) and poly(B-benzyl L-aspartate) Langmuir 1993, 9, 945– 949.
    OpenUrlCrossRefWeb of Science
  4. 4.↵
    1. Yokoyama M.,
    2. Miyauchi M.,
    3. Yamada N.,
    4. Okano T.,
    5. SaKurai Y.,
    6. Kataoka K.,
    7. Inoue S.
    Polymer micelles as novel drug carrier: adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. J. Controlled Release 1990, 11 ( 1–3), 269– 278.
    OpenUrlCrossRefWeb of Science
  5. 5.↵
    1. Singer J. W.,
    2. Bhatt R.,
    3. Tulinsky J.,
    4. Buhler K. R.,
    5. Heasley E.,
    6. Klein P.,
    7. Vries P.
    Water soluble poly-(L glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo. J. Controlled Release 2001, 74, 243– 247.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Cortesi R.,
    2. Esposito E.,
    3. Maietti A.,
    4. Manegatti E,
    5. Nastruzzi C.
    Formulation study for the antitumor drug camptothecin: liposomes, micellar solution and microemulsion. Int. J. Pharm. 1997, 159, 95– 103.
    OpenUrl
  7. 7.↵
    1. Yang S. C.,
    2. Lu L. F.,
    3. Cai Y.,
    4. Zhu J. B.,
    5. Liang B. W.,
    6. Yang C. Z.
    Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain. J. Controlled Release 1999, 59, 299– 307.
    OpenUrlPubMed
  8. 8.↵
    1. Ilium L.
    Chitosan its use as pharmaceutical excipient. Pharm. Res. 1998, 15, 1326– 1361.
    OpenUrlCrossRefPubMedWeb of Science
  9. 9.↵
    1. Lehr C.-M.,
    2. Bouwstra J. A.,
    3. Schacht E. H.,
    4. Junginger H. E.
    In vitro evaluation of mucosdhesive properties of chitosan and some other natural polymers. Int. J. Pharm. 1992, 78, 43– 48.
    OpenUrlCrossRef
  10. 10.↵
    1. Artursson P.,
    2. Lindmark T.,
    3. Davis S. S.,
    4. Ilium L.
    Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2). Pharm. Res. 1994, 11, 1358– 1361.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.↵
    1. Ilium L.,
    2. Farraj N. F.,
    3. Davis S. S.
    Chitosan as novel nasal delivery system for peptide drugs. Pharm. Res. 1994, 11, 1186– 1189.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    1. Miwa A.,
    2. Ishibe A.,
    3. Nakano M.,
    4. Yamahira T.,
    5. Itai S.,
    6. Jinno S.,
    7. Kawahara H.
    Development of novel chitosan derivatives as a micellar carriers of texol. Pharm. Res. 1998, 15, 1844– 1850.
    OpenUrlPubMed
  13. 13.↵
    1. Zhang C.,
    2. Ping Q.,
    3. Zhang H.,
    4. Shen J.
    Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of texol. Carbohydrate Polymers 2003, 54, 137– 141.
    OpenUrlCrossRefWeb of Science
  14. 14.↵
    1. Uchegbu I. F.,
    2. Sadiq L.,
    3. Arastoo M.,
    4. Gray A. I.,
    5. Wang W.,
    6. Waigh R. D.,
    7. Schatzleina A. G.
    Quaternary ammonium palmitoyl glycol chitosan—a new polysoap for drug delivery. Int. J. Pharm. 2001, 224 ( 1), 85– 199.
    OpenUrl
  15. 15.↵
    1. Wang W.,
    2. McConaghy A. M.,
    3. Tetlay L.,
    4. Uchegbu I. F.
    Controll on molecular weight may be used to control the size of palmitoyl glycol chitosan polymeric vesicles. Langmuir 2001, 17 ( 3), 631– 636.
    OpenUrl
  16. 16.↵
    1. Samina R. M.
    S. Thesis. Glycol chitosan solubilizer: A high throughput method of selection. University of Strayhclyde, Glasgow, Scotland, 2003.
  17. 17.↵
    1. Beijnen J. H.,
    2. Roasing H.,
    3. Bokkel Huinink W. W.
    High-performance liquid chromatography analysis of the antitumour drug camptothecin and its lactone ring-opened form in rat plasma. J. Chromatogr. 1993, 617 ( 1), 11– 117.
    OpenUrlPubMed
  18. 18.↵
    1. Loh J. P.,
    2. Ahmad A. E.
    Determination of camptothecin in biological fluid using reversed phase high-performance liquid chromatography with fluorescence detection. J. Chromatogr. 1990, 530, 367– 376.
    OpenUrlPubMed
  19. 19.↵
    1. Bevan C. D.,
    2. Lloyd R. S.
    A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates. Anal. Chem. 2000, 72, 1781– 1787.
    OpenUrlPubMed
  20. 20.↵
    1. Petro M.,
    2. Nguyen S. H.,
    3. Liu M.,
    4. Kolosov O.
    Combinatorial exploration of polymeric transport agents for targeted delivery of bioactive to human tissues: Macromolecular Rapid Communications 2004, 25 ( 1), 178– 188.
    OpenUrl
  21. 21.↵
    1. Chen H.,
    2. Zhang Z.,
    3. McNulty C.,
    4. Olbert C.,
    5. Yoon H. J.,
    6. Lee J. W.,
    7. Kim S. C.,
    8. Seo M. H.,
    9. Oh H. S.,
    10. Lemmo A. V.,
    11. Ellis S. J.,
    12. Heimlich K.
    A high-throughput combinatorial approach for the discovery of cremophor EL-Free paclitaxel formulation. Pharm. Res. 2003, 20, 1302– 1308.
    OpenUrlPubMed
  22. 22.↵
    1. Opanasopit P.,
    2. Yokoyama M.,
    3. Watanable M.,
    4. Kawano K.,
    5. Maitani Y.,
    6. Okano T.
    Block copolymer design for camptothecin incorporation into polymeric micelles for passive tumor targeting. Pharm. Res. 2004, 21, 2001– 2008.
    OpenUrlPubMed
  23. 23.↵
    1. Cochin D.,
    2. De Schryver F. C.,
    3. Laschewsky A.,
    4. Stam J. V.
    Polysoaps in aqueous solutions: Intermolecular versus intramolecular hydrophobic aggregation studied by fluorescence spectroscopy. Langmuir 2001, 17, 2579– 2584
    OpenUrl
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PDA Journal of Pharmaceutical Science and Technology
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January/February 2009
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Polymeric Micelles of Ammonium Palmitoyl Glycol Chitosan and Solubilization of Camptothecin
Nazar M. Ranjha
PDA Journal of Pharmaceutical Science and Technology Jan 2009, 63 (1) 81-87;

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Polymeric Micelles of Ammonium Palmitoyl Glycol Chitosan and Solubilization of Camptothecin
Nazar M. Ranjha
PDA Journal of Pharmaceutical Science and Technology Jan 2009, 63 (1) 81-87;
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