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- Published online October 3, 2012.
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© PDA, Inc. 2012
Author Information
- 1Department of Pharmaceutics, KCT'S RGS College of Pharmacy, Anjaneri, Nashik, Maharashtra, India;
- 2Department of Pharmaceutics, S.M.B.T. College of Pharmacy, Dhamangaon, Nashik, Maharashtra, India; and
- 3Department of Pharmaceutics, Vishnu College of Pharmaceutical Education and Reaserch, Medak, Hyderabad, AP, India
- ↵*Correspondence author: Shinkar Dattatraya Manohar, Aai, Row House No. 1, Ganraj Row Houses, Laxmi Nagar, Mahale Farm, Near Ranapratap Chawk, Cidco, Nashik. 422 009, Maharashtra, India. Mobile telephone: +91-9921842402. E-mail: dattashinkar@gmail.com
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- Article
- Abstract
- Introduction
- Advantages of the Mucoadhesive Buccal Drug Delivery System
- Limitations of the Mucoadhesive Buccal Drug Delivery System
- Anatomy and Structure of the Oral Cavity
- Composition of Mucus Layer
- Functions of the Mucus Layer
- Structure of the Oral Mucosa
- Buccal Absorption
- Assessing Drug Permeation through the Buccal Mucosa
- Buccal Penetration Enhancers (31, 32)
- Classification and Examples of Membrane Permeation Enhancers
- Mechanism of Permeation Enhancers
- Bioadhesion/Mucoadhesion
- Mechanism of Mucoadhesion/Bioadhesion
- Theories on Mucoadhesion/Bioadhesion
- Factors Affecting Mucoadhesion
- Buccal Mucoadhesive Polymers
- Ideal Characteristics of Buccal Mucoadhesive Polymers (24)
- New-Generation Mucoadhesive Polymers
- Buccal Mucoadhesive Dosage Forms
- General Considerations in Designing Dosage Forms
- Approaches to the Use of Mucoadhesive Formulations
- Relevant Mucoadhesive Buccal Dosage Forms
- Evaluation of Mucoadhesive Buccal Drug Delivery Systems
- In Vitro Techniques
- Work of Adhesion
- Other In Vitro Methods
- In Vivo Techniques
- Method
- Ex Vivo Residence Time
- In Vivo Residence Time
- Current Market Status of Buccal Drug Delivery Systems
- Conclusion
- Conflict of Interest Declaration
- Acknowldgements
- References
- Figures & Data
- References
- Info & Metrics