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Research ArticleTechnology/Application

A Method Utilizing Ultra-High Performance Liquid Chromatography with Ultraviolet and Mass Spectrometric Detection for the Analysis of Material Extracts Produced during a Controlled Extraction Study

Steven A. Zdravkovic, Matthew D. Bruss, Robert F. Piccoli and Derek M. Wood
PDA Journal of Pharmaceutical Science and Technology September 2014, 68 (5) 504-526; DOI: https://doi.org/10.5731/pdajpst.2014.00992
Steven A. Zdravkovic
cGMP Laboratory, Pharmaceutical Product Development, Inc. (PPD), 8551 Research Way, Suite 90, Middleton, WI 53562, United States
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  • For correspondence: Steve.Zdravkovic@ppdi.com
Matthew D. Bruss
cGMP Laboratory, Pharmaceutical Product Development, Inc. (PPD), 8551 Research Way, Suite 90, Middleton, WI 53562, United States
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Robert F. Piccoli
cGMP Laboratory, Pharmaceutical Product Development, Inc. (PPD), 8551 Research Way, Suite 90, Middleton, WI 53562, United States
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Derek M. Wood
cGMP Laboratory, Pharmaceutical Product Development, Inc. (PPD), 8551 Research Way, Suite 90, Middleton, WI 53562, United States
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PDA Journal of Pharmaceutical Science and Technology: 68 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 68, Issue 5
September/October 2014
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A Method Utilizing Ultra-High Performance Liquid Chromatography with Ultraviolet and Mass Spectrometric Detection for the Analysis of Material Extracts Produced during a Controlled Extraction Study
Steven A. Zdravkovic, Matthew D. Bruss, Robert F. Piccoli, Derek M. Wood
PDA Journal of Pharmaceutical Science and Technology Sep 2014, 68 (5) 504-526; DOI: 10.5731/pdajpst.2014.00992

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A Method Utilizing Ultra-High Performance Liquid Chromatography with Ultraviolet and Mass Spectrometric Detection for the Analysis of Material Extracts Produced during a Controlled Extraction Study
Steven A. Zdravkovic, Matthew D. Bruss, Robert F. Piccoli, Derek M. Wood
PDA Journal of Pharmaceutical Science and Technology Sep 2014, 68 (5) 504-526; DOI: 10.5731/pdajpst.2014.00992
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Keywords

  • Extractables
  • Leachables
  • UHPLC/UV/MS
  • LC/MS
  • controlled extraction study

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