Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Jeffrey R. Vieregg; Steven J. Martin; Adam P. Breeland; Christopher M. Weikart; Matthew V. Tirrell

doi:10.5731/pdajpst.2017.008011

Research ArticleResearch

Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Jeffrey R. Vieregg, Steven J. Martin, Adam P. Breeland, Christopher M. Weikart and Matthew V. Tirrell

PDA Journal of Pharmaceutical Science and Technology January 2018, 72 (1) 35-43; DOI: https://doi.org/10.5731/pdajpst.2017.008011

Jeffrey R. Vieregg

1Institute for Molecular Engineering, University of Chicago, Chicago, IL;

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Steven J. Martin

2SiO Medical Products, Auburn, AL; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Adam P. Breeland

2SiO Medical Products, Auburn, AL; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Christopher M. Weikart

2SiO Medical Products, Auburn, AL; and

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Matthew V. Tirrell

1Institute for Molecular Engineering, University of Chicago, Chicago, IL;

3Institute for Molecular Engineering, Argonne National Laboratory, Argonne, IL

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: mtirrell@uchicago.edu

Article
Figures & Data
References
Info & Metrics
PDF

Article Information

vol. 72 no. 1 35-43

DOI

https://doi.org/10.5731/pdajpst.2017.008011

PubMed

28928291

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online January 30, 2018.

Article Versions

previous version (September 19, 2017 - 05:22).
You are viewing the most recent version of this article.

Author Information

Jeffrey R. Vieregg1,
Steven J. Martin2,
Adam P. Breeland2,
Christopher M. Weikart2 and
Matthew V. Tirrell1,3,*

¹Institute for Molecular Engineering, University of Chicago, Chicago, IL;
²SiO₂ Medical Products, Auburn, AL; and
³Institute for Molecular Engineering, Argonne National Laboratory, Argonne, IL

↵*Corresponding Author: University of Chicago, ERC 299C, 5640 S. Ellis Ave., Chicago, IL 60637. Telephone: 773-834-2001; e-mail: mtirrell{at}uchicago.edu

View Full Text

Cited By...

8 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Development of syringes and vials for delivery of biologics: current challenges and innovative solutions

Saki Yoneda, Tetsuo Torisu, Susumu Uchiyama

Expert Opinion on Drug Delivery 2021 18 4
High Sensitivity Plasmonic Sensing of Hydrogen over a Broad Dynamic Range Using Catalytic Au-CeO2 Thin Film Nanocomposites

Nora M. Houlihan, Nicholas Karker, Radislav A. Potyrailo, Michael A. Carpenter

ACS Sensors 2018 3 12
Hybrid Blood Collection Tubes: Combining the Best Attributes of Glass and Plastic for Safety and Shelf life

Christopher M. Weikart, Adam P. Breeland, Matt S. Wills, Martin E. Baltazar-Lopez

SLAS Technology 2020 25 5
Essentials of Industrial Pharmacy

Muhammad Naseer Abbas, Waqar Iqbal, Shahzeb Khan

2022 46
Exploring the complexities of drug formulation selection, storage, and shelf‐life for exploration spaceflight

Vernie R. Daniels, Edward S. Williams

British Journal of Clinical Pharmacology 2024
Impact of protein adsorption during biopharmaceutical manufacture & storage

John D. Downey, Abina M. Crean, Katie B. Ryan

European Journal of Pharmaceutical Sciences 2025 209
Impact of vial quality on interactions, particle formation, container closure integrity, and gas permeability for frozen drug product storage

Daniela Henle, Lukas Muehlfeld, Daniel Molnar, Patrick Garidel, Wolfgang Friess

European Journal of Pharmaceutical Sciences 2025 206
Protein Instability at Interfaces During Drug Product Development

Susan Jordan, Jim Curtis, Lloyd Waxman

2021 43

PreviousNext

In This Issue

PDA Journal of Pharmaceutical Science and Technology

Vol. 72, Issue 1

January/February 2018

Table of Contents
Index by Author

Download PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for your interest in spreading the word on PDA Journal of Pharmaceutical Science and Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Message Subject (Your Name) has sent you a message from PDA Journal of Pharmaceutical Science and Technology

Message Body (Your Name) thought you would like to see the PDA Journal of Pharmaceutical Science and Technology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Math question * 9 + 4 =

Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.

Citation Tools

Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Jeffrey R. Vieregg, Steven J. Martin, Adam P. Breeland, Christopher M. Weikart, Matthew V. Tirrell

PDA Journal of Pharmaceutical Science and Technology Jan 2018, 72 (1) 35-43; DOI: 10.5731/pdajpst.2017.008011

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Jeffrey R. Vieregg, Steven J. Martin, Adam P. Breeland, Christopher M. Weikart, Matthew V. Tirrell

PDA Journal of Pharmaceutical Science and Technology Jan 2018, 72 (1) 35-43; DOI: 10.5731/pdajpst.2017.008011

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
References
Info & Metrics
PDF

No related articles found.

PubMed
Google Scholar

Cited By...

No citing articles found.

Google Scholar

Keywords

Primary containers
oxidation
permeation
Sterilization
Teriparatide
Erythropoietin

Main menu

User menu

Search

Inhibiting Sterilization-Induced Oxidation of Large Molecule Therapeutics Packaged in Plastic Parenteral Vials

Article Information

Article Versions

Author Information

Cited By...

In This Issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

Readers

Author/Reviewer Information

Parenteral Drug Association, Inc.