Applying Machine Learning to the Visual Inspection of Filled Injectable Drug Products

Romain Veillon; John Shabushnig; Lars Aabye-Hansen; Matthieu Duvinage; Christian Eckstein; Zheng Li; Andrea Sardella; Manuel Soto; Jorge Delgado Torres; Brian Turnquist

doi:10.5731/pdajpst.2022.012796

Research ArticleTechnology/Application

Applying Machine Learning to the Visual Inspection of Filled Injectable Drug Products

Romain Veillon, John Shabushnig, Lars Aabye-Hansen, Matthieu Duvinage, Christian Eckstein, Zheng Li, Andrea Sardella, Manuel Soto, Jorge Delgado Torres and Brian Turnquist

PDA Journal of Pharmaceutical Science and Technology September 2023, 77 (5) 376-401; DOI: https://doi.org/10.5731/pdajpst.2022.012796

Romain Veillon

1GSK, Wavres, Belgium;

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John Shabushnig

2Insight Pharma Consulting, LLC, Marshall, MI;

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For correspondence: JohnShabushnig@aol.com

Lars Aabye-Hansen

3Novo Nordisk, Copenhagen, Denmark;

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Matthieu Duvinage

1GSK, Wavres, Belgium;

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Christian Eckstein

4MVTec GmbH, München, Germany;

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Zheng Li

5Genentech, South San Francisco, CA;

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Andrea Sardella

6Stevanato Group, S.p.a., Vicenza, Italy;

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Manuel Soto

7Amgen, Juncos, Puerto Rico; and

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Jorge Delgado Torres

7Amgen, Juncos, Puerto Rico; and

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Brian Turnquist

8BoonLogic, Inc., St Paul, MN

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vol. 77 no. 5 376-401

DOI

https://doi.org/10.5731/pdajpst.2022.012796

PubMed

37321861

Published By

Parenteral Drug Association (PDA)

Print ISSN

1079-7440

Online ISSN

1948-2124

History

Published online October 6, 2023.

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previous version (June 15, 2023 - 12:15).
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Author Information

Romain Veillon¹,
John Shabushnig²,*,
Lars Aabye-Hansen³,
Matthieu Duvinage¹,
Christian Eckstein⁴,
Zheng Li⁵,
Andrea Sardella⁶,
Manuel Soto⁷,
Jorge Delgado Torres⁷ and
Brian Turnquist⁸

¹GSK, Wavres, Belgium;
²Insight Pharma Consulting, LLC, Marshall, MI;
³Novo Nordisk, Copenhagen, Denmark;
⁴MVTec GmbH, München, Germany;
⁵Genentech, South San Francisco, CA;
⁶Stevanato Group, S.p.a., Vicenza, Italy;
⁷Amgen, Juncos, Puerto Rico; and
⁸BoonLogic, Inc., St Paul, MN

↵*Corresponding Author: 15630 17 1/2 Mile Rd, Marshall, MI 49068; Telephone: 1+ 269-277-0012; E-mail: JohnShabushnig{at}aol.com

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Applying Machine Learning to the Visual Inspection of Filled Injectable Drug Products

Romain Veillon, John Shabushnig, Lars Aabye-Hansen, Matthieu Duvinage, Christian Eckstein, Zheng Li, Andrea Sardella, Manuel Soto, Jorge Delgado Torres, Brian Turnquist

PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 376-401; DOI: 10.5731/pdajpst.2022.012796

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Applying Machine Learning to the Visual Inspection of Filled Injectable Drug Products

Romain Veillon, John Shabushnig, Lars Aabye-Hansen, Matthieu Duvinage, Christian Eckstein, Zheng Li, Andrea Sardella, Manuel Soto, Jorge Delgado Torres, Brian Turnquist

PDA Journal of Pharmaceutical Science and Technology Sep 2023, 77 (5) 376-401; DOI: 10.5731/pdajpst.2022.012796

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Keywords

visual inspection
Automated inspection
Injectable drug
machine learning
Deep learning
Supervised learning
Unsupervised learning
Image labeling
Neural network
Inspection qualification

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