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Research ArticleResearch

Time Temperature Superposition Evaluation and Modeling for Container Closure System's Seal Performance at Low Temperatures

Qingyu Zeng, Anthony Bucci and Le Ho
PDA Journal of Pharmaceutical Science and Technology January 2020, 74 (1) 27-40; DOI: https://doi.org/10.5731/pdajpst.2019.010371
Qingyu Zeng
West Pharmaceutical Services, Inc, Exton, PA 19341
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  • For correspondence: qingyu.zeng@westpharma.com
Anthony Bucci
West Pharmaceutical Services, Inc, Exton, PA 19341
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Le Ho
West Pharmaceutical Services, Inc, Exton, PA 19341
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In This Issue

PDA Journal of Pharmaceutical Science and Technology: 74 (1)
PDA Journal of Pharmaceutical Science and Technology
Vol. 74, Issue 1
January/February 2020
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Time Temperature Superposition Evaluation and Modeling for Container Closure System's Seal Performance at Low Temperatures
Qingyu Zeng, Anthony Bucci, Le Ho
PDA Journal of Pharmaceutical Science and Technology Jan 2020, 74 (1) 27-40; DOI: 10.5731/pdajpst.2019.010371
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  • Article
    • Abstract
    • Introduction
    • Experimental Testing Setup
    • Experimental Testing and Modeling Evaluation Results and Discussion
    • Conclusion
    • Conflict of Interest Declaration
    • Acknowledgments
    • References
  • Figures & Data
  • References
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  • Evaluation of Extreme Depyrogenation Conditions on the Surface Hydrolytic Resistance of Glass Containers for Pharmaceutical Use
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Keywords

  • Compression stress relaxation (CSR)
  • Residual seal force (RSF)
  • Container closure system (CCS)
  • Container closure integrity (CCI)
  • Stopper
  • Vial
  • Cap
  • Seal
  • Capping
  • Time-dependent
  • Temperature-dependent
  • Maxwell–Wiechert model
  • Kohlrausch–Williams–Watts (KWW) stretched exponential function
  • Time–temperature superposition
  • Arrhenius
  • Williams–Landel–Ferry (WLF)

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Time Temperature Superposition Evaluation and Modeling for Container Closure System's Seal Performance at Low Temperatures
Qingyu Zeng, Anthony Bucci, Le Ho
PDA Journal of Pharmaceutical Science and Technology Jan 2020, 74 (1) 27-40; DOI: 10.5731/pdajpst.2019.010371

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