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Research ArticleResearch

A New Integrated Modeling Approach with Case Studies for Gas Transmission of Container Closure Headspace

Qingyu Zeng
PDA Journal of Pharmaceutical Science and Technology September 2021, 75 (5) 394-406; DOI: https://doi.org/10.5731/pdajpst.2020.012351
Qingyu Zeng
West Pharmaceutical Services, Inc.
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  • For correspondence: qingyu.zeng@westpharma.com
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References

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    1. Victor K. G.,
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    Container Closure Integrity Testing—Method Development for Freeze-Dried Products Using Laser-Based Headspace Oxygen Analysis. PDA J. Pharm. Sci. Technol. 2019, 73 (2), 170–180.
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PDA Journal of Pharmaceutical Science and Technology: 75 (5)
PDA Journal of Pharmaceutical Science and Technology
Vol. 75, Issue 5
September/October 2021
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A New Integrated Modeling Approach with Case Studies for Gas Transmission of Container Closure Headspace
Qingyu Zeng
PDA Journal of Pharmaceutical Science and Technology Sep 2021, 75 (5) 394-406; DOI: 10.5731/pdajpst.2020.012351

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A New Integrated Modeling Approach with Case Studies for Gas Transmission of Container Closure Headspace
Qingyu Zeng
PDA Journal of Pharmaceutical Science and Technology Sep 2021, 75 (5) 394-406; DOI: 10.5731/pdajpst.2020.012351
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Cited By...

  • A Container Closure Integrity Test Method for Vials Stored at Cryogenic Conditions Using Headspace Oxygen Analysis
  • Container Closure Integrity Test Method Development on Vials Stored at -80{degrees}C Using Headspace Carbon Dioxide Analysis
  • A Multicompany Survey Study for Helium Leak Container Closure Integrity Test
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  • Evaluation of Extreme Depyrogenation Conditions on the Surface Hydrolytic Resistance of Glass Containers for Pharmaceutical Use
  • A Holistic Approach for Filling Volume Variability Evaluation and Control with Statistical Tool
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Keywords

  • Container closure system (CCS)
  • Container closure integrity (CCI)
  • Diffusion
  • Mass and volumetric flow
  • Fick's law
  • Darcy–Weisbach equation

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